Pernix Ireland Pain Designated Activity Company (the “Issuer”) is a designated activity company limited by shares incorporated on 19 March 2015 under the laws of Ireland (registration number 559207). The Issuer is a direct and wholly owned subsidiary of Pernix Therapeutics Holdings, Inc. (organizational identification number D04539888), having its registered office at 10 North Park Place, Suite 201, Morristown, NJ 07960, United States. The Issuer’s registered office is located at 3 Burlington Road, Dublin 4, Ireland and its telephone number is 1-800-793-2145.

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